BDBM50303323 (2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]-amino}ethyl)phosphinyl]-(2R)-2-[(3-phenylisoxazol-5-yl)methyl]-1-oxopropyl}amino)1H-Indole-3-propanoic Acid::CHEMBL577754

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1cc(no1)-c1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=ITMFWUAKJPURIP-NINLVYDZSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303323   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  8nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  36nMAssay Description:Inhibition of human somatic ACE in presence of bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  500nMAssay Description:Inhibition of human somatic ACE in presence of 1:100 diluted SHR rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of human somatic ACE in presence of 1:100 diluted SHR rat plasma complemented with 5 uM serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of human somatic ACE in presence of 1:50 diluted SHR rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL
LigandPNGBDBM50303323((2S)-2-({3-[Hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)...)
Affinity DataKi:  1.85E+3nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed