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BDBM50303374 3-Benzyl-3-ethyl-1-phenylazetidine-2,4-dione::CHEMBL578583

SMILES: CCC1(Cc2ccccc2)C(=O)N(C1=O)c1ccccc1

InChI Key: InChIKey=FWZVCEYFFJOHOK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50303374   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukocyte elastase


(Homo sapiens (Human))
BDBM50303374
PNG
(3-Benzyl-3-ethyl-1-phenylazetidine-2,4-dione | CHE...)
Show SMILES CCC1(Cc2ccccc2)C(=O)N(C1=O)c1ccccc1
Show InChI InChI=1S/C18H17NO2/c1-2-18(13-14-9-5-3-6-10-14)16(20)19(17(18)21)15-11-7-4-8-12-15/h3-12H,2,13H2,1H3
PDB
MMDB

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Similars

Article
PubMed
127n/an/an/an/an/an/an/an/a



University of Lisbon

Curated by ChEMBL


Assay Description
Inhibition of human leukocyte elastase after 20 mins


J Med Chem 53: 241-53 (2010)


Article DOI: 10.1021/jm901082k
BindingDB Entry DOI: 10.7270/Q23B607D
More data for this
Ligand-Target Pair