BDBM50303409 4-amino-6-(diphenylamino)-1,3,5-triazine-2-carbonitrile::CHEMBL577764::cid_712283

SMILES Nc1nc(nc(n1)N(c1ccccc1)c1ccccc1)C#N

InChI Key InChIKey=KTIBTQAECPZEKI-UHFFFAOYSA-N

Data  1 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50303409   

TargetD(1A) dopamine receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataEC50:  0.00588nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataKi:  180nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataIC50: 2.99E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetCathepsin S(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataIC50: 5.84E+3nMAssay Description:Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataEC50:  6.66E+4nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50303409(cid_712283 | CHEMBL577764 | 4-amino-6-(diphenylami...)
Affinity DataEC50:  1.63E+5nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay