BDBM50303410 4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5-triazine-2-carbonitrile::CHEMBL567785

SMILES Clc1cccc(Nc2nc(NC3CCCC3)nc(n2)C#N)c1

InChI Key InChIKey=QNUYHZAYXDMWMT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50303410   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  79nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  851nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin Z(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  6.46E+3nMAssay Description:Inhibition of human Cathepsin X/ZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-14(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human Caspase 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  513nMAssay Description:Inhibition of papaya papainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of human Caspase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed