BDBM50303692 CHEMBL565988::Thiophene-2-sulfonic Acid{(E)-3-[1-(3,4-Dimethylbenzyl)-1H-indol-7-y l]acryloyl}amide

SMILES Cc1ccc(Cn2ccc3cccc(\C=C\C(=O)NS(=O)(=O)c4cccs4)c23)cc1C

InChI Key InChIKey=BMDNYIKPUSORHV-ZHACJKMWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303692   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303692(CHEMBL565988 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  71nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303692(CHEMBL565988 | Thiophene-2-sulfonic Acid{(E)-3-[1-...)
Affinity DataIC50:  4.22E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed