BDBM50303732 5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluoromethoxy-phenyl)-3,5-diydro-imidazol-4-one::CHEMBL583899

SMILES: CN1C(N)=NC(C1=O)(c1ccc(OC(F)(F)F)cc1)C12CC3CC(CC(C3)C1)C2

InChI Key:

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50303732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM50303732 (5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM50303732 (5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 2 (Human)	BDBM50303732 (5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM50303732 (5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM50303732 (5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair