BDBM50303734 (S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one::CHEMBL571320

SMILES: COc1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)C12CC3CC(CC(C3)C1)C2

InChI Key:

Data: 7 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50303734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 2 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin D (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 2 (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin D (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Renin (Human)	BDBM50303734 ((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
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