BDBM50304245 6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]-4H-chromen-4-one::CHEMBL594229

SMILES COc1cc2occ(-c3ccc(cc3)N3CCCC3)c(=O)c2cc1OC

InChI Key InChIKey=KJFTVNFZEUSHFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304245   

TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50304245(6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50304245(6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50304245(6,7-Dimethoxy-3-[4-(pyrrolidin-1-ylmethyl)-phenyl]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed