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BDBM50304615 CHEMBL593738::N-(benzo[c][1,2,5]oxadiazol-4-yl)-3-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide

SMILES: COc1cccc(\C=C2/SC(=S)N(CCC(=O)Nc3cccc4nonc34)C2=O)c1

InChI Key: InChIKey=PWUJUZBGURGBGJ-WJDWOHSUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304615   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor 1 (FIH)


(Homo sapiens (Human))
BDBM50304615
PNG
(CHEMBL593738 | N-(benzo[c][1,2,5]oxadiazol-4-yl)-3...)
Show SMILES COc1cccc(\C=C2/SC(=S)N(CCC(=O)Nc3cccc4nonc34)C2=O)c1
Show InChI InChI=1S/C20H16N4O4S2/c1-27-13-5-2-4-12(10-13)11-16-19(26)24(20(29)30-16)9-8-17(25)21-14-6-3-7-15-18(14)23-28-22-15/h2-7,10-11H,8-9H2,1H3,(H,21,25)/b16-11-
PDB

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.31E+4n/an/an/an/an/an/a



Sejong University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FIH1


Bioorg Med Chem 17: 7769-74 (2009)


Article DOI: 10.1016/j.bmc.2009.09.034
BindingDB Entry DOI: 10.7270/Q2TM7B6R
More data for this
Ligand-Target Pair