BDBM50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689

SMILES Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F

InChI Key InChIKey=ZDUOYBOFMKORCT-UHFFFAOYSA-N

Data  8 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50305077   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta-LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRbeta expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  31nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataEC50:  183nMAssay Description:Agonist activity at human Gal4-LBD fused LXRbeta LBD expressed in Huh7 cells by transient transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRalpha-LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRalpha expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305077(3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]T0901317 from human recombinant LXRbeta LBDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed