BDBM50305090 (+/-)-6-fluoro-9-(3-(5-fluoro-1H-indol-3-yl)propylamino)-2,3,4,8,9,10-hexahydro-1H-pyrano[2,3-h]isoquinolin-1-one::CHEMBL595744

SMILES Fc1ccc2[nH]cc(CCCNC3COc4c(F)cc5CCNC(=O)c5c4C3)c2c1

InChI Key InChIKey=NFJKAVIMGUBTOG-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305090   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305090((+/-)-6-fluoro-9-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305090((+/-)-6-fluoro-9-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  27nMAssay Description:Displacement of labeled paroxetine from 5-HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305090((+/-)-6-fluoro-9-(3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed