BDBM50305291 (3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)piperidin-4-yl)-9H-purin-2-yl)phenyl)methanol::CHEMBL583228

SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncn(C3CCN(Cc4ccc(cc4)-c4ccncc4)CC3)c2n1

InChI Key InChIKey=IUQYTHJFTMSDAO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305291   

LigandPNGBDBM50305291((3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)pipe...)
Affinity DataIC50:  23nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305291((3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)pipe...)
Affinity DataIC50:  720nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305291((3-(6-morpholino-9-(1-(4-(pyridin-4-yl)benzyl)pipe...)
Affinity DataIC50:  223nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed