BDBM50305295 5-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)pyridin-3-ol::CHEMBL590619

SMILES Oc1cncc(c1)-c1nc(N2CCOCC2)c2ncn(C3CCNCC3)c2n1

InChI Key InChIKey=VLNLIVDYHRPHDN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305295   

LigandPNGBDBM50305295(5-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305295(5-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  970nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305295(5-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  44nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed