BDBM50305316 3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-2-one::CHEMBL592043

SMILES Oc1ccc2c(c(Cc3ccccc3)c(=O)oc2c1)C(F)(F)F

InChI Key InChIKey=BBWVBLPWIQCZOJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305316   

Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at ER by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at AR by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed