BDBM50305549 3-(4-(3,6-dihydro-2H-pyran-4-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenol::CHEMBL601054

SMILES Oc1cccc(c1)-c1nc(C2=CCOCC2)c2cnn(-c3ccccc3)c2n1

InChI Key InChIKey=HOKDCTJUGJPQRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305549   

LigandPNGBDBM50305549(3-(4-(3,6-dihydro-2H-pyran-4-yl)-1-phenyl-1H-pyraz...)
Affinity DataIC50:  59nMAssay Description:Inhibition of PI3Kalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305549(3-(4-(3,6-dihydro-2H-pyran-4-yl)-1-phenyl-1H-pyraz...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mTOR in HEK293 cells by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed