BDBM50305569 CHEMBL590597::N-(5-bromothiazol-2-ylcarbamoyl)-5-(4-methoxy-2-methylphenyl)-4-methylthiophene-2-sulfonamide

SMILES COc1ccc(-c2sc(cc2C)S(=O)(=O)NC(=O)Nc2ncc(Br)s2)c(C)c1

InChI Key InChIKey=KCBMMYUZSJZEEC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305569   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305569(CHEMBL590597 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305569(CHEMBL590597 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305569(CHEMBL590597 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed