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BDBM50305654 4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine::CHEMBL593514

SMILES: C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1

InChI Key: InChIKey=YMMOIRWTLTTWOB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305654   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))
BDBM50305654
PNG
(4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine | CHEMB...)
Show SMILES C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1
Show InChI InChI=1S/C13H13N5O2/c1-4-20-7-9(1)11-16-12-10(14-8-15-12)13(17-11)18-2-5-19-6-3-18/h1,4,7-8H,2-3,5-6H2,(H,14,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assay


Bioorg Med Chem Lett 20: 636-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.051
BindingDB Entry DOI: 10.7270/Q2V98852
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50305654
PNG
(4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine | CHEMB...)
Show SMILES C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1
Show InChI InChI=1S/C13H13N5O2/c1-4-20-7-9(1)11-16-12-10(14-8-15-12)13(17-11)18-2-5-19-6-3-18/h1,4,7-8H,2-3,5-6H2,(H,14,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.79E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assay


Bioorg Med Chem Lett 20: 636-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.051
BindingDB Entry DOI: 10.7270/Q2V98852
More data for this
Ligand-Target Pair