BDBM50305737 CHEMBL604277::N,N'-(1,2-phenylene)bis(N-allyl-4-methylbenzenesulfonamide)

SMILES Cc1ccc(cc1)S(=O)(=O)N(CC=C)c1ccccc1N(CC=C)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=WLHVFPKZYDQKGS-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50305737   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50:  300nMAssay Description:Displacement of [125I]human anaphylatoxin C5a from human C5a receptor expressed in CHO cells co-expressed with Galpha16 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human P2Y2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CXCR4 in human T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50: >6.00E+4nMAssay Description:Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CXCR3 in human T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305737(CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-m...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed