BDBM50305841 CHEMBL605201::N1,N3-bis(3-methoxybenzyl)isophthalamide

SMILES COc1cccc(CNC(=O)c2cccc(c2)C(=O)NCc2cccc(OC)c2)c1

InChI Key InChIKey=XDBOLPFDJWTESQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50305841   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305841(CHEMBL605201 | N1,N3-bis(3-methoxybenzyl)isophthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed