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BDBM50305916 (S)-2-(4-Chloro-phenyl)-N-[5-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-thiazol-2-yl]-3,3-dimethyl-butyramide::CHEMBL594507

SMILES: CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCS(=O)(=O)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=JIGYQRKEQHMNGA-XISACWJONA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305916   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50305916
PNG
((S)-2-(4-Chloro-phenyl)-N-[5-(1,1-dioxo-1lambda*6*...)
Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCS(=O)(=O)CC1)c1ccc(Cl)cc1
Show InChI InChI=1/C19H24ClN3O3S2/c1-19(2,3)16(13-4-6-14(20)7-5-13)17(24)22-18-21-12-15(27-18)23-8-10-28(25,26)11-9-23/h4-7,12,16H,8-11H2,1-3H3,(H,21,22,24)/t16-/s2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair