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BDBM50305926 (S)-2-(4-chlorophenyl)-N-(thiazol-2-yl)pent-4-enamide::CHEMBL594738

SMILES: Clc1ccc(cc1)[C@H](CC=C)C(=O)Nc1nccs1

InChI Key: InChIKey=HSOAIKDJQLYYGH-STGVRZAANA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305926   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50305926
PNG
((S)-2-(4-chlorophenyl)-N-(thiazol-2-yl)pent-4-enam...)
Show SMILES Clc1ccc(cc1)[C@H](CC=C)C(=O)Nc1nccs1
Show InChI InChI=1/C14H13ClN2OS/c1-2-3-12(10-4-6-11(15)7-5-10)13(18)17-14-16-8-9-19-14/h2,4-9,12H,1,3H2,(H,16,17,18)/t12-/s2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair