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BDBM50305981 (S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3-methylbutanamide::CHEMBL611339

SMILES: CC(C)[C@H](C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc1

InChI Key: InChIKey=CPDXIHHGJDEMTJ-STGVRZAANA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305981   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50305981
PNG
((S)-2-(4-chlorophenyl)-N-(5-chlorothiazol-2-yl)-3-...)
Show SMILES CC(C)[C@H](C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc1
Show InChI InChI=1/C14H14Cl2N2OS/c1-8(2)12(9-3-5-10(15)6-4-9)13(19)18-14-17-7-11(16)20-14/h3-8,12H,1-2H3,(H,17,18,19)/t12-/s2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production


Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair