BDBM50306633 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea::CHEMBL601661

SMILES: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C3CCC4(CC3)OCCO4)c2n1

InChI Key: InChIKey=QLHHRYZMBGPBJG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50306633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase SMG1 (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50306633 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair