BDBM50307127 (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE::(Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide::CHEMBL605003::N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide::SU-6656

SMILES: CN(C)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1

InChI Key: InChIKey=LOGJQOUIVKBFGH-UHFFFAOYSA-N

Data: 18 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50307127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase C (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase LCK (Mouse)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase BRSK2 (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Chicken)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Yes (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.88E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Human)	BDBM50307127 ((Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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