BDBM50307141 (Z)-3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-5-furan-3-yl-1,3-dihydro-indol-2-one::CHEMBL602073

SMILES Cc1cc(C)c(\C=C2/C(=O)Nc3ccc(cc23)-c2occc2C)[nH]1

InChI Key InChIKey=ORFSHJKFXCCOCT-YBEGLDIGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307141   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50307141((Z)-3-(3,5-Dimethyl-1H-pyrrol-2-ylmethylene)-5-fur...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant His-tagged RET expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed