BDBM50307168 5-((biphenyl-3-ylthio)methyl)furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL604090

SMILES Nc1nc(N)c2c(CSc3cccc(c3)-c3ccccc3)coc2n1

InChI Key InChIKey=HKQLLSDRBFXVOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307168   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307168(5-((biphenyl-3-ylthio)methyl)furo[2,3-d]pyrimidine...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307168(5-((biphenyl-3-ylthio)methyl)furo[2,3-d]pyrimidine...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed