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BDBM50307203 2-Chloro-6-methyl-N-(3-morpholinopropyl)nicotinamide::CHEMBL597762

SMILES: Cc1ccc(C(=O)NCCCN2CCOCC2)c(Cl)n1

InChI Key: InChIKey=DAZBKULXHSFEAP-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307203   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50307203
PNG
(2-Chloro-6-methyl-N-(3-morpholinopropyl)nicotinami...)
Show SMILES Cc1ccc(C(=O)NCCCN2CCOCC2)c(Cl)n1
Show InChI InChI=1S/C14H20ClN3O2/c1-11-3-4-12(13(15)17-11)14(19)16-5-2-6-18-7-9-20-10-8-18/h3-4H,2,5-10H2,1H3,(H,16,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of MAOA in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorometry


Bioorg Med Chem 18: 1659-64 (2010)


Article DOI: 10.1016/j.bmc.2009.12.065
BindingDB Entry DOI: 10.7270/Q22F7NKV
More data for this
Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B)


(Rattus norvegicus (rat))
BDBM50307203
PNG
(2-Chloro-6-methyl-N-(3-morpholinopropyl)nicotinami...)
Show SMILES Cc1ccc(C(=O)NCCCN2CCOCC2)c(Cl)n1
Show InChI InChI=1S/C14H20ClN3O2/c1-11-3-4-12(13(15)17-11)14(19)16-5-2-6-18-7-9-20-10-8-18/h3-4H,2,5-10H2,1H3,(H,16,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of MAOB in Sprague-Dawley rat brain mitochondria using kynuramine substrate by fluorometry


Bioorg Med Chem 18: 1659-64 (2010)


Article DOI: 10.1016/j.bmc.2009.12.065
BindingDB Entry DOI: 10.7270/Q22F7NKV
More data for this
Ligand-Target Pair