BDBM50307375 CHEMBL589377::N-[(1S,2S,4R)-1-(3,5-difluorophenoxymethyl)-2-hydroxy-4-methoxy-4-phenylcarbamoylbutyl]-5-(methanesulfonyl-methyl-amino)-N'-((R)-1-phenyl-ethyl)-isophthalamide

SMILES CO[C@H](C[C@H](O)[C@H](COc1cc(F)cc(F)c1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)CS(C)(=O)=O)C(=O)Nc1ccccc1

InChI Key InChIKey=QPUGHQRBULQGOP-CZCCDBLPSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307375   

TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307375(CHEMBL589377 | N-[(1S,2S,4R)-1-(3,5-difluorophenox...)
Affinity DataKi:  200nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307375(CHEMBL589377 | N-[(1S,2S,4R)-1-(3,5-difluorophenox...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed