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BDBM50307803 4-Acetamidophenyl 3-(2-(trifluoromethyl)pyridin-4-ylamino)benzoate::CHEMBL598165

SMILES: CC(=O)Nc1ccc(OC(=O)c2cccc(Nc3ccnc(c3)C(F)(F)F)c2)cc1

InChI Key: InChIKey=YEKHVXWOOFZKJV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307803   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Rattus norvegicus (rat))
BDBM50307803
PNG
(4-Acetamidophenyl 3-(2-(trifluoromethyl)pyridin-4-...)
Show SMILES CC(=O)Nc1ccc(OC(=O)c2cccc(Nc3ccnc(c3)C(F)(F)F)c2)cc1
Show InChI InChI=1S/C21H16F3N3O3/c1-13(28)26-15-5-7-18(8-6-15)30-20(29)14-3-2-4-16(11-14)27-17-9-10-25-19(12-17)21(22,23)24/h2-12H,1H3,(H,25,27)(H,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.70E+4n/an/an/an/an/an/a



University of Cagliari

Curated by ChEMBL


Assay Description
Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopy


J Med Chem 53: 2286-98 (2010)


Article DOI: 10.1021/jm901891p
BindingDB Entry DOI: 10.7270/Q2833S4K
More data for this
Ligand-Target Pair