BDBM50307942 4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide::CHEMBL598194::US8796293, 69

SMILES: c1cc(ccc1CNC(=O)C2(CCN(CC2)c3c4cc[nH]c4ncn3)N)Cl

InChI Key: InChIKey=XQPFDQVEBGYLHB-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50307942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	7.5	25
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Cytochrome P450 1A2 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-beta serine/threonine-protein kinase (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-beta serine/threonine-protein kinase (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-gamma serine/threonine-protein kinase (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50307942 (CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
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