BDBM50307989 4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5-ene-2-carbonyl)-amino]-thiophene-3-carboxylic acid isopropylester::CHEMBL598217

SMILES CC(C)OC(=O)c1c(NC(=O)C2C3CC(C=C3)C2C(O)=O)scc1-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PGQNLABOVUNFPI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50307989   

TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPalpha expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LAR expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50307989(4-Biphenyl-4-yl-2-[(3-carboxy-bicyclo[2.2.1]hept-5...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of TCPTP expressed in Escherichia coli BL21 (DE3) after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed