BDBM50308138 1-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)-3-(piperidin-1-yl)urea::CHEMBL597012

SMILES O=C(NN1CCCCC1)Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1

InChI Key InChIKey=TWCCZQFICQQJLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308138   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308138BDBM50308138(1-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)-...)
Affinity DataIC50: 460nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50308138BDBM50308138(1-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)-...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50308138BDBM50308138(1-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)-...)
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed