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BDBM50308419 CHEMBL589536::N-[2-(Pyrrolidinyl)ethyl]-10H-phenothiazine-10-carboxamide

SMILES: O=C(NCCN1CCCC1)N1c2ccccc2Sc2ccccc12

InChI Key: InChIKey=DUFNIJJWDMNBKO-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308419   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholinesterases


(Homo sapiens (Human))
BDBM50308419
PNG
(CHEMBL589536 | N-[2-(Pyrrolidinyl)ethyl]-10H-pheno...)
Show SMILES O=C(NCCN1CCCC1)N1c2ccccc2Sc2ccccc12
Show InChI InChI=1S/C19H21N3OS/c23-19(20-11-14-21-12-5-6-13-21)22-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)22/h1-4,7-10H,5-6,11-14H2,(H,20,23)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
210n/an/an/an/an/an/an/an/a



Dalhousie University

Curated by ChEMBL


Assay Description
Inhibition of human plasma BuChE by modified Ellman's spectrophotometric method


Bioorg Med Chem 18: 2232-44 (2010)


Article DOI: 10.1016/j.bmc.2010.01.066
BindingDB Entry DOI: 10.7270/Q21C1X08
More data for this
Ligand-Target Pair
Cholinesterases


(Homo sapiens (Human))
BDBM50308419
PNG
(CHEMBL589536 | N-[2-(Pyrrolidinyl)ethyl]-10H-pheno...)
Show SMILES O=C(NCCN1CCCC1)N1c2ccccc2Sc2ccccc12
Show InChI InChI=1S/C19H21N3OS/c23-19(20-11-14-21-12-5-6-13-21)22-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)22/h1-4,7-10H,5-6,11-14H2,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.94E+4n/an/an/an/an/an/an/an/a



Dalhousie University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant AChE by modified Ellman's spectrophotometric method


Bioorg Med Chem 18: 2232-44 (2010)


Article DOI: 10.1016/j.bmc.2010.01.066
BindingDB Entry DOI: 10.7270/Q21C1X08
More data for this
Ligand-Target Pair