BDBM50308557 3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL591501

SMILES: CCCOCCn1c2cc(ncc2nc(N2CCN(CCO)CC2)c1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=MNLNAGRCHNMKKJ-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50308557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50308557 (3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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