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BDBM50308926 4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)benzamide::CHEMBL589588

SMILES: COc1ccc(NC(=O)c2ccc(cc2)N(CCCl)CCCl)cc1

InChI Key: InChIKey=ZTIZNUWTTGLAGF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308926   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))
BDBM50308926
PNG
(4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)ben...)
Show SMILES COc1ccc(NC(=O)c2ccc(cc2)N(CCCl)CCCl)cc1
Show InChI InChI=1S/C18H20Cl2N2O2/c1-24-17-8-4-15(5-9-17)21-18(23)14-2-6-16(7-3-14)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant HER2 expressed in Sf9-baculovirus system by ELISA


Bioorg Med Chem 18: 880-6 (2010)


Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50308926
PNG
(4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)ben...)
Show SMILES COc1ccc(NC(=O)c2ccc(cc2)N(CCCl)CCCl)cc1
Show InChI InChI=1S/C18H20Cl2N2O2/c1-24-17-8-4-15(5-9-17)21-18(23)14-2-6-16(7-3-14)22(12-10-19)13-11-20/h2-9H,10-13H2,1H3,(H,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of recombinant EGFR expressed in Sf9-baculovirus system by ELISA


Bioorg Med Chem 18: 880-6 (2010)


Article DOI: 10.1016/j.bmc.2009.11.037
BindingDB Entry DOI: 10.7270/Q2WH2Q3N
More data for this
Ligand-Target Pair