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BDBM50309433 2-(4-(4-methoxyphenyl)-2-(phenylamino)thiazol-5-yl)acetic acid::CHEMBL609898

SMILES: COc1ccc(cc1)-c1nc(Nc2ccccc2)sc1CC(O)=O

InChI Key: InChIKey=YAPOORUUUYSFGP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309433   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50309433
PNG
(2-(4-(4-methoxyphenyl)-2-(phenylamino)thiazol-5-yl...)
Show SMILES COc1ccc(cc1)-c1nc(Nc2ccccc2)sc1CC(O)=O
Show InChI InChI=1S/C18H16N2O3S/c1-23-14-9-7-12(8-10-14)17-15(11-16(21)22)24-18(20-17)19-13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,19,20)(H,21,22)
PDB

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UniProtKB/SwissProt

DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...


Bioorg Med Chem Lett 20: 1177-80 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.008
BindingDB Entry DOI: 10.7270/Q25T3KMP
More data for this
Ligand-Target Pair
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50309433
PNG
(2-(4-(4-methoxyphenyl)-2-(phenylamino)thiazol-5-yl...)
Show SMILES COc1ccc(cc1)-c1nc(Nc2ccccc2)sc1CC(O)=O
Show InChI InChI=1S/C18H16N2O3S/c1-23-14-9-7-12(8-10-14)17-15(11-16(21)22)24-18(20-17)19-13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,19,20)(H,21,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cells


Bioorg Med Chem Lett 20: 1177-80 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.008
BindingDB Entry DOI: 10.7270/Q25T3KMP
More data for this
Ligand-Target Pair