BDBM50309518 2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)pyridine::CHEMBL598561

SMILES COc1cccc(F)c1Oc1ncccc1C1CCNCC1

InChI Key InChIKey=ATVZOYVGUWYSKX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309518   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309518(2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309518(2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...)
Affinity DataKi:  276nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309518(2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...)
Affinity DataKi:  887nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309518(2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...)
Affinity DataKi:  6.41E+3nMAssay Description:Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed