BindingDB logo
myBDB logout

BDBM50309530 2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-methoxybenzofuran-3-yl)-N,N-dimethyl-2-oxoacetamide::CHEMBL597428

SMILES: COc1cc2occ(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1

InChI Key: InChIKey=WZBZMSAWTLRHEF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309530   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50309530
PNG
(2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...)
Show SMILES COc1cc2occ(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C26H27FN2O5/c1-28(2)26(32)24(30)21-15-34-23-14-22(33-3)20(13-19(21)23)25(31)29-10-8-17(9-11-29)12-16-4-6-18(27)7-5-16/h4-7,13-15,17H,8-12H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 600n/an/an/an/an/an/a



Scios, Inc

Curated by ChEMBL


Assay Description
Inhibition of human p38alpha after 60 mins


Bioorg Med Chem Lett 20: 1059-62 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.031
BindingDB Entry DOI: 10.7270/Q2J38SP4
More data for this
Ligand-Target Pair