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BDBM50309635 CHEMBL599676::N-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)-2-(2-fluorophenoxy)acetamide

SMILES: Fc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(Cl)ccc2o1

InChI Key: InChIKey=RPKUSUNFXKQAES-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309635   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM50309635
PNG
(CHEMBL599676 | N-(4-(5-chlorobenzo[d]oxazol-2-yl)p...)
Show SMILES Fc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C21H14ClFN2O3/c22-14-7-10-19-17(11-14)25-21(28-19)13-5-8-15(9-6-13)24-20(26)12-27-18-4-2-1-3-16(18)23/h1-11H,12H2,(H,24,26)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CETP assessed as cholesteryl ester transfer activity


Bioorg Med Chem Lett 20: 1019-22 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.046
BindingDB Entry DOI: 10.7270/Q2MW2H8Q
More data for this
Ligand-Target Pair