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BDBM50309641 1-benzyl-3-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)urea::CHEMBL598765

SMILES: Clc1ccc2oc(nc2c1)-c1ccc(NC(=O)NCc2ccccc2)cc1

InChI Key: InChIKey=WQNDAGAMUNDEQE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309641   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM50309641
PNG
(1-benzyl-3-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)...)
Show SMILES Clc1ccc2oc(nc2c1)-c1ccc(NC(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C21H16ClN3O2/c22-16-8-11-19-18(12-16)25-20(27-19)15-6-9-17(10-7-15)24-21(26)23-13-14-4-2-1-3-5-14/h1-12H,13H2,(H2,23,24,26)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CETP assessed as cholesteryl ester transfer activity


Bioorg Med Chem Lett 20: 1019-22 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.046
BindingDB Entry DOI: 10.7270/Q2MW2H8Q
More data for this
Ligand-Target Pair