BDBM50309680 (2S,6S,2R)-2-[6-(2-(2-Thiophene)-sulfonyloxy-2-phenylethyl)-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride::CHEMBL605748

SMILES CN1[C@H](C[C@H](OS(=O)(=O)c2cccs2)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1

InChI Key InChIKey=SSRKNCDKTZOVPB-CUYJMHBOSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309680   

TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309680((2S,6S,2R)-2-[6-(2-(2-Thiophene)-sulfonyloxy-2-phe...)
Affinity DataKi:  4.23E+3nMAssay Description:Displacement of [3HDTBZ from VMAT2 in rat whole brain vesicles by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309680((2S,6S,2R)-2-[6-(2-(2-Thiophene)-sulfonyloxy-2-phe...)
Affinity DataKi:  1.81E+4nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309680((2S,6S,2R)-2-[6-(2-(2-Thiophene)-sulfonyloxy-2-phe...)
Affinity DataKi:  1.99E+4nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed