BDBM50309861 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]-nonane::CHEMBL604798::CP-810123
SMILES Cc1ccc2oc(nc2n1)N1CCN2CCC1CC2
InChI Key InChIKey=BSNKYWSMUAGMDO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50309861
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 13.5nMAssay Description:Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16.4nMAssay Description:Displacement of [125I]BTX from human alpha7 nicotinic acetylcholine receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of muscarinic M4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nMAssay Description:Inhibition of muscarinic M5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of muscarinic M3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Agonist activity at human 5HT3 receptor expressed in human skin epithelial cells assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair