BDBM50309910 CHEMBL608154::ML-120B::N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide

SMILES: COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C

InChI Key: InChIKey=ZNOLRTPMNMPLHY-UHFFFAOYSA-N

Data: 2 IC50  442 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 450 hits for monomerid = 50309910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	465	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase BRSK1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 11A (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit beta (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Hepatocyte growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Protein kinase C eta type (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 6 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-6 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent protein kinase 1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Macrophage-stimulating protein receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TNNI3K (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 3 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Hepatocyte growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-2 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Misshapen-like kinase 1 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK gamma (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50309910 (N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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