BDBM50309914 2-cyclohexyl-3-oxoisoindoline-4-carboxamide::CHEMBL597888::cid_5309879

SMILES NC(=O)c1cccc2CN(C3CCCCC3)C(=O)c12

InChI Key InChIKey=AEDVPHAKDUNUHG-UHFFFAOYSA-N

Data  1 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309914   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309914(CHEMBL597888 | cid_5309879 | 2-cyclohexyl-3-oxoiso...)
Affinity DataKi:  172nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309914(CHEMBL597888 | cid_5309879 | 2-cyclohexyl-3-oxoiso...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of PARP1 in human C41 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50309914(CHEMBL597888 | cid_5309879 | 2-cyclohexyl-3-oxoiso...)
Affinity DataIC50: 1.25E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50309914(CHEMBL597888 | cid_5309879 | 2-cyclohexyl-3-oxoiso...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay