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BDBM50310348 4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide::CHEMBL598449

SMILES: COc1ccc(cc1)-n1ncc(c1N)-c1ccc(cc1)C(N)=O

InChI Key: InChIKey=DLJOTMUYQOUVAT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))
BDBM50310348
PNG
(4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Show SMILES COc1ccc(cc1)-n1ncc(c1N)-c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C17H16N4O2/c1-23-14-8-6-13(7-9-14)21-16(18)15(10-20-21)11-2-4-12(5-3-11)17(19)22/h2-10H,18H2,1H3,(H2,19,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.25E+4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of human MK2 by FRET assay


Bioorg Med Chem Lett 20: 1293-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.138
BindingDB Entry DOI: 10.7270/Q2MP53C5
More data for this
Ligand-Target Pair