BDBM50310818 3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)piperidine-1-carboxamide::CHEMBL1077780

SMILES CC1(CCCN(C1)C(=O)N[C@H]1C[C@@H]1c1ccccc1)c1ccccc1

InChI Key InChIKey=UUJAMNFWDAPMSE-MFCMXAAESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310818   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310818(3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)p...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310818(3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpoxide hydrolase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310818(3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human microsomal epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310818(3-methyl-3-phenyl-N-((1S,2R)-2-phenylcyclopropyl)p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed