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BDBM50310973 3-bromo-4-(4-fluorobenzyloxy)-6-methyl-1-(pyridin-3-yl)pyridin-2(1H)-one::CHEMBL1080220

SMILES: Cc1cc(OCc2ccc(F)cc2)c(Br)c(=O)n1-c1cccnc1

InChI Key: InChIKey=XYQSURDVJCTREQ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310973   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 9


(Homo sapiens (Human))
BDBM50310973
PNG
(3-bromo-4-(4-fluorobenzyloxy)-6-methyl-1-(pyridin-...)
Show SMILES Cc1cc(OCc2ccc(F)cc2)c(Br)c(=O)n1-c1cccnc1
Show InChI InChI=1S/C18H14BrFN2O2/c1-12-9-16(24-11-13-4-6-14(20)7-5-13)17(19)18(23)22(12)15-3-2-8-21-10-15/h2-10H,11H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Pfizer Corporation

Curated by ChEMBL


Assay Description
Inhibition of JNK2


Bioorg Med Chem Lett 19: 5851-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.082
BindingDB Entry DOI: 10.7270/Q2HM59DG
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50310973
PNG
(3-bromo-4-(4-fluorobenzyloxy)-6-methyl-1-(pyridin-...)
Show SMILES Cc1cc(OCc2ccc(F)cc2)c(Br)c(=O)n1-c1cccnc1
Show InChI InChI=1S/C18H14BrFN2O2/c1-12-9-16(24-11-13-4-6-14(20)7-5-13)17(19)18(23)22(12)15-3-2-8-21-10-15/h2-10H,11H2,1H3
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



Pfizer Corporation

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


Bioorg Med Chem Lett 19: 5851-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.082
BindingDB Entry DOI: 10.7270/Q2HM59DG
More data for this
Ligand-Target Pair