BDBM50310998 CHEMBL1077458::N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)phenyl)acetamide

SMILES: CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key: InChIKey=RMBHIVQOFNFWFU-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Human)	BDBM50310998 (N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50310998 (N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	795	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50310998 (N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	975	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50310998 (N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>980	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50310998 (N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)ph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair