BDBM50311544 2-(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)piperidin-4-yl)ethoxy)-5-fluoropyrimidin-4-amine::CHEMBL1079768

SMILES Nc1nc(OCCC2CCN(CC2)c2cc(ncn2)-c2cc3ccccc3s2)ncc1F

InChI Key InChIKey=KZTOEDJNXONIBZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311544   

TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311544(2-(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311544(2-(2-(1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)p...)
Affinity DataEC50:  160nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosohorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed