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BDBM50311733 2-(chroman-3-yl)-6-(1H-pyrazol-4-yl)-4-(2-(tetrahydrofuran-3-yl)ethoxy)benzo[d]thiazole::CHEMBL1080265

SMILES: C(CC1CCOC1)Oc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1

InChI Key: InChIKey=ZHSQTINQSPGGQO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311733   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50311733
PNG
(2-(chroman-3-yl)-6-(1H-pyrazol-4-yl)-4-(2-(tetrahy...)
Show SMILES C(CC1CCOC1)Oc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1
Show InChI InChI=1/C25H25N3O3S/c1-2-4-21-17(3-1)9-19(15-31-21)25-28-24-22(30-8-6-16-5-7-29-14-16)10-18(11-23(24)32-25)20-12-26-27-13-20/h1-4,10-13,16,19H,5-9,14-15H2,(H,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Translational Research Institute and Department of Molecular Therapeutics

Curated by ChEMBL


Assay Description
Inhibition of ROCK2


Bioorg Med Chem Lett 19: 6686-90 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.115
BindingDB Entry DOI: 10.7270/Q2VX0GN0
More data for this
Ligand-Target Pair